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Serum levels of insulin-like growth factor-1 and insulin-like growth factor-1 binding proteins after radical prostatectomy. Interestingly, certain polymorphisms in the insulin gene have been associated with an increased risk of prostate cancer. Although it is easily determined, BMI has its limitations. Based on their findings, Giovannucci and colleagues 31 argued that tumors in younger men and those with a family history of prostate cancer may be driven by increased androgens and, thus, the lower androgen levels seen in men with obesity may have been protective against prostate cancer. Recent advances in basic obesity research. The relationship among obesity, its physiologic sequelae, and the risk of prostate cancer is unclear. Reduced risk of prostate cancer among patients with diabetes mellitus.

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Given the protracted course of prostate cancer, it is thought that events that occur earlier in life may predispose to prostate cancer later in life. Cellular actions of insulin-like growth factor binding proteins. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. Body size and prostate cancer: a year follow-up study among , Swedish construction workers.

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