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The nude mouse has been proposed as a model animal for testing the chemosensitivity of human cancer cells, and encouraging results have been obtained. Murine brain tumor models were successfully prepared by direct inoculation of glioma cells into the cerebral hemisphere, an immunologically privileged area. However, the blood-brain barrier was destroyed mechanically by this manipulation.

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If the address matches an existing account you will receive an email with instructions to reset your password. If the address matches an existing account you will receive an email with instructions to retrieve your username. Search for more papers by this author.

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Filter publications by model type: All. Chat with us. Wang J, et al.

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He is considered the most important Spanish artist of the late 18th and early 19th centuries and throughout his long career was a commentator and chronicler of his era. Immensely successful in his lifetime, Goya is often referred to as both the last of the Old Masters and the first of the moderns. He was also one of the great portraitists of his time.

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When comedian Whitney Cummings faced demands for money over a revealing picture, she simply tweeted the picture herself, taunting her would-be blackmailers. It's a powerful lesson in emotional intelligence and in how to stand up to online bullies. The internet in general, and Twitter in particular, is not always a friendly place for high-profile women.

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Although surgical resection is the standard treatment modality for HCC, its use is limited, as the majority of patients, even in those with small-sized tumors, also have associated severe liver dysfunction 23. Liver transplantation provides an alternative curative treatment for small unresectable HCC in patients with small-sized tumors. However, the shortage of liver grafts limits the applicability of this approach 4.

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Metrics details. Angiopoietin-2 Ang-2 plays critical roles in vascular morphogenesis and its upregulation is frequently associated with various tumors. Previous studies showed that certain selenium compounds possess anti-tumor effects.

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Salma Hayek celebrated a social media milestone with a nude photo — and fans can't get enough. The actress garnered 12 million followers on Instagram and celebrated the feat with a special post on Monday. You have gotten me to the 12 million!!! A needle for health and well-being representing each million of you.

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The development of multi-agent chemotherapy has improved outcome [ 3 — 6 ], but is not effective for ES patients with metastasis [ 7 ]. Furthermore, the heterogeneity of ES makes the treatment decisions much more complicated [ 89 ]. ES recurred in the bone marrow of the patient 19 months after primary tumor resection and DOX treatment.

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The ostensible subject of ''Tatjana in Color,'' an adventurous historical drama by Julia Jordan, is the inner life of adolescent girls. Set in in Neulengbach, a small Austrian town 20 miles from Vienna, it is based on an episode in the life of the artist Egon Schiele, who was jailed for obscenity for using an under-age girl as a nude model. Jordan's play, written in and being presented for the first time in New York by the Culture Project at 45 Bleecker Street, depicts the circumstances of Schiele's arrest and his subsequent release when suspicions he had raped the girl were unproved. But Schiele, then a year-old iconoclast and libertine and played by Glenn Fitzgerald with appropriately pretentious self-regard, is actually a minor character in the play.


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